The CCBC brings together an interdisciplinary research team to interrogate the cross-cutting properties of Bacterial Microcompartments (BMCs) that are fundamental and hence relevant to both biological and synthetic energy chemistries.
The CCBC's research efforts are organized into three linked Thrusts. Each Thrust area deals with a distinct set of themes related to properties of bacterial microcompartments, for which increased understanding of biological fundamentals will lead directly to enhanced abilities to engineer these systems. Thrust areas work in parallel to one another and are organized by progressively higher scales of organization.
Thrust 1 research will address structure and physical-chemical characterization combined with computational modeling to resolve fundamental mechanisms by which protein shell subunits determine BMC assembly and create microenvironments tuned for specialized catalysis.